Abruzzi, Sucre and C-Note make a run for it on their own; Michael and Lincoln plan another breakout this time to rescue a jailed LJ, whom Mahone targets in his quest to capture the escaped cons; Bellick and Warden Pope face a jury of their peers regarding the prison escape; Tweener hitches a ride with [...]

Picking up eight hours after their escape from Fox River, Michael, Lincoln, Sucre, Abruzzi and C-Note are on the run for their lives as a vengeful Bellick leads the prison guards seeking to capture their escaped quarry; Dr. Sara is in critical condition from her overdose; Veronica finds herself a prisoner with Terrance; T-Bag tries [...]

With the escape in motion, Michael, Lincoln and the inmates take flight outside the prison walls, risking life and limb to evade capture. Warden Pope and Captain Bellick embark on a relentless pursuit to capture the escapees; the Vice President fears she will lose her command as well as her life; and Veronica tracks down [...]

The mystery man reveals himself to Lincoln as well as his connection to some bad company; when Michael realizes Sara holds the key to the escape plan, he takes their relationship to another level; Fox River turns into a mob scene when a familiar face returns; Tweener must choose sides; and Bellick may finally discover [...]

Transferred to the psych ward, Michael tries to clear Haywire’s head and jog his memory of the missing piece of the blueprint tattoo; Bellick wants to auction off Michael’s cell to the highest bidder; C-Note and T-Bag must team up in a high-stakes poker game, while Sucre’s cousin Manche seems to hold all the cards.
Prison [...]